Explain how changes in PpH and temperature lead to denaturation of proteins
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Explain how changes in PpH and temperature lead to denaturation of proteins
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Answer:
Changes in pH affect the chemistry of amino acid residues and can lead to denaturation. ... Protonation of the amino acid residues (when an acidic proton H + attaches to a lone pair of electrons on a nitrogen) changes whether or not they participate in hydrogen bonding, so a change in the pH can denature a protein.